1 reply, 2 voices Last updated by Jennis 2 months ago
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    • #24779

      shailender
      Participant
      @shailender

      Salbutamol (also known as albuterol) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of respiratory conditions like asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart.

      Indications

      Salbutamol is indicated for the relief of:

      Bronchospasm
      Bronchospasm in asthma
      Any other cause of bronchospasm, such as:
      Anaphylaxis
      Smoke inhalation
      Pulmonary edema
      Pneumonia
      Bronchitis
      Shortness of breath with expiratory wheeze
      Salbutamol is contraindicated in cases of:

      Hypersensitivity
      Severe pre-eclampsia
      Uterine bleeding
      Premature membrane rupture with chorioamnionitis
      Pregnancy
      Adverse effects

      Increase in heart rate- this is dose-dependent, but is rarely a major problem.

      Hypotension may occur.

      By affecting pulmonary mismatch, can cause increased hypoxia and hence, pulse oximetry and supplemental oxygen should be used.

      Fine tremor is seen in about 20% of patients.

      Less common reactions are such as nausea, vomiting, and dizziness

      Most common side effects-fine tremor, anxiety, headache, muscle cramps, dry mouth, and palpitation.

      Drug interactions-Special warnings/precautions for use

      Bronchodilators should not be the only or primary treatment for severe or unstable asthma.

      Increasing bronchodilator use, especially short-acting inhaled beta2-agonists to relieve symptoms indicates deterioration of asthma control. If patients find that short-acting relief bronchodilator treatment becomes less effective or they need more inhalations than usual, immediate medical intervention is recommended.

      Salbutamol causes peripheral vasodilation which may result in reflex tachycardia and increased cardiac output

      Hyperthyroidism- Salbutamol should only be administered cautiously to patients suffering from thyrotoxicosis after careful evaluation of the benefits and risks of treatment.

      Constant monitoring of potassium levels in patients with severe asthma is essential; potentially serious hypokalaemia may result from beta-2 agonist therapy.https://wcts.app/huNxBR

    • #24830

      Jennis
      Participant
      @JennisFr

      Hello! Thank you for the helpful and informative article here! As for me, I often use Canadian Pharmacy for information about different medicine and how to buy it online. I am pretty sure that you will find it helpful to you too, good luck!

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