1 reply, 2 voices Last updated by  Jennis 1 week, 1 day ago
  • Author
    Posts
  • #24779

    shailender
    Participant
    @shailender

    Salbutamol (also known as albuterol) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of respiratory conditions like asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart.

    Indications

    Salbutamol is indicated for the relief of:

    Bronchospasm
    Bronchospasm in asthma
    Any other cause of bronchospasm, such as:
    Anaphylaxis
    Smoke inhalation
    Pulmonary edema
    Pneumonia
    Bronchitis
    Shortness of breath with expiratory wheeze
    Salbutamol is contraindicated in cases of:

    Hypersensitivity
    Severe pre-eclampsia
    Uterine bleeding
    Premature membrane rupture with chorioamnionitis
    Pregnancy
    Adverse effects

    Increase in heart rate- this is dose-dependent, but is rarely a major problem.

    Hypotension may occur.

    By affecting pulmonary mismatch, can cause increased hypoxia and hence, pulse oximetry and supplemental oxygen should be used.

    Fine tremor is seen in about 20% of patients.

    Less common reactions are such as nausea, vomiting, and dizziness

    Most common side effects-fine tremor, anxiety, headache, muscle cramps, dry mouth, and palpitation.

    Drug interactions-Special warnings/precautions for use

    Bronchodilators should not be the only or primary treatment for severe or unstable asthma.

    Increasing bronchodilator use, especially short-acting inhaled beta2-agonists to relieve symptoms indicates deterioration of asthma control. If patients find that short-acting relief bronchodilator treatment becomes less effective or they need more inhalations than usual, immediate medical intervention is recommended.

    Salbutamol causes peripheral vasodilation which may result in reflex tachycardia and increased cardiac output

    Hyperthyroidism- Salbutamol should only be administered cautiously to patients suffering from thyrotoxicosis after careful evaluation of the benefits and risks of treatment.

    Constant monitoring of potassium levels in patients with severe asthma is essential; potentially serious hypokalaemia may result from beta-2 agonist therapy.https://wcts.app/huNxBR

  • #24830

    Jennis
    Participant
    @JennisFr

    Hello! Thank you for the helpful and informative article here! As for me, I often use Canadian Pharmacy for information about different medicine and how to buy it online. I am pretty sure that you will find it helpful to you too, good luck!

You must be logged in to reply to this topic.